Biology White Papers
Role of Cell Cycle
Overview
An understanding of the role of cell cycle was essential at two points in the development of the nuclear transfer techniques which are used at present: the definition of the importance of MPF activity in the recipient oocyte and the use of donor cells in quiescence.
Taken together these observations suggest that there is a window during the donor cell cycle in which nuclear transfer is more effective. This window includes mitosis, G1 and G0 and effective comparisons between these phases have not yet been made. In addition, there is an advantage in adjusting the time of activation in relation to nuclear transfer. Much remains to be learned as to how to improve the present procedures.
| Publisher | National Institute of Standards and Technology | File Format | HTML |
|---|---|---|---|
| Date Published | August 2003 | ||
| Format | White Papers | ||
| Topics | |||
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